Pearlie was born April 24, 1950 to the parents of Dee Ellis Mosley and Moline Hughes Mosley, in Winston County Mississippi.
Pearlie was preceded in death by her husband, Wesley Lewis, Jr. parents, Dee Ellis and Moline Mosley; sister, Bessie Diane Brown.
Pearlie is survived by her children, Karen Lewis, Donald Lewis, and Derrick "Bo" Lewis (Lamesha); Brother, Dee Ellis Mosley, Jr., (Patricia); (14) grandchildren, (11) great grandchildren; a host of nieces, nephews, cousins and other relatives and family.